Virtual biotech operating model

A virtual biotech for evidence-led drug discovery.

Chief Orchestrator, specialist scientific agents and an independent Red Team connect opportunity selection to Candidate OS and MIDD — with humans retaining decision authority.

Open Opportunity Scout View architecture
Evidence linked Red-team challenged Human governed
1Chief Orchestrator coordinating the virtual company
7Core discovery specialist roles in the current scientific structure
6Governed stages from scientific state to lifecycle learning
0Autonomous consequential approvals — humans remain authoritative
Operating boundary: Opportunity Scout is connected to a live read-only prioritisation backend. The Mission Room is still a guided simulation. Agent reasoning is advisory: scientific tools, evidence provenance, audit controls and qualified human review remain authoritative.
Opportunity layerLive scoutEvidence-weighted triage with transparent scoring.
Reasoning layerSynthesis + challengeSpecialist reasoning separated from contradiction review.
Scientific executionTool governedModels and calculations remain outside free-form agent authority.
Decision authorityHuman gatedNo consequential programme approval is autonomous.
Opportunity scouting

Surface disease, target and modality hypotheses before resources are committed.

Evidence linked

Keep claims, sources, uncertainty and contradictions connected through the programme.

Independent challenge

Red-Team reasoning tests assumptions, alternative explanations and failure modes.

Human governed

Agents prepare decisions; qualified humans remain authoritative at consequential gates.

Lifecycle continuity

Opportunity, Discovery, Candidate OS and MIDD stay connected instead of becoming isolated analyses.

BayesArc capability map

One frontend over the systems we already have.

This view does not create a second scientific platform. It exposes the existing BayesArc, Agent OS, Discovery Twin, Candidate OS and MIDD capabilities as one company-level experience while the backend integration is completed later.

LIVE

Opportunity Scout

Evidence-weighted opportunity prioritisation with contradictions, unknowns, falsifiers and Red-Team context.

PRESENT

Agent OS + Discovery Programme Manager

Programme-scoped orchestration, specialist fan-out, durable runs, evidence packages and human approvals already exist in BayesArc.

PRESENT

Discovery Twin

Programme hypotheses, evidence claims, causal graphs, contradictions, credibility, experiments and governed decision state.

PRESENT

Discovery Red Team

Independent critique of specialist findings, opposing evidence, unresolved gaps and failure modes before progression.

PRESENT

BayesArc Discovery Execution

Target evidence, generation, docking, ADMET, developability, retrosynthesis and experimental handoff remain in the existing discovery stack.

PRESENT

Candidate OS

Candidate identity, evidence ledger, profile thresholds, decision lifecycle and governed nomination already exist.

PRESENT

MIDD

Programme-linked quantitative development, model orchestration and review-gated translational workflows.

FRONTEND NOW

Virtual Biotech Control Plane

Unified mission identity, company timeline and cross-system orchestration are represented here first. Backend wiring will follow without changing current client-facing APIs.

OpportunityScout and frame the scientific opportunity.
OrchestrateChief Orchestrator and Programme Manager define the work graph.
SpecialistsBiology, chemistry, DMPK, translation and feasibility work in bounded lanes.
ChallengeIndependent Red Team surfaces contradictions and falsifiers.
Commit evidenceDiscovery Twin / evidence graph becomes the scientific state.
Human gateQualified reviewer decides advance, close gaps, redesign, pause or stop.
Continue lifecycleBayesArc → Candidate OS → MIDD → Clinical Development.
Frontend-only integration phase: this page currently presents the unified company experience and links to existing live BayesPharma capabilities. It does not create a new programme, change an existing client record, trigger scientific compute, or alter current backend workflows.
Organization

The virtual company hierarchy.

This page brings the existing leadership-agent idea and discovery scientist organization into one company-level operating model. The hierarchy is explicit so strategy, science, review, and authority do not collapse into one agent.

LEADERSHIP AGENT OS

Company orchestration layer

Leadership roles coordinate business, science, technology, governance, and model quality.

Chief OrchestratorSingle synthesis point for multi-agent company workstreams.
Agent CEOStrategy, priorities, partnerships, milestones.
Agent CTOArchitecture, APIs, reliability, security posture.
Agent CFORunway, pricing, cost and scenario discipline.
Drug Discoverer AgentTarget biology, docking, ADMET, synthesis, experiments.
Regulatory & QualityClaims, validation, readiness and review gates.
AI/ML EngineerModel evaluation, uncertainty, active learning.
Product SMEProduct boundaries and module fidelity.
Improvement LoopFeedback, traces, failures, and evaluation learning.
SCIENTIFIC COMPANY

Discovery scientist organization

The programme manager delegates a mission to bounded domain scientists and an independent red team.

Discovery Programme ManagerCreates the stage-aware plan, assigns specialists, and frames the decision gate.
Opportunity ScoutUnmet need, landscape and opportunity framing.
Disease Biology & Target EvidenceCausal rationale and biological evidence.
Medicinal ChemistryDesign, optimization and chemistry hypotheses.
DMPK & DevelopabilityExposure, ADME and developability liabilities.
Translational & Clinical EvidenceHuman relevance, biomarkers and clinical signals.
Portfolio & FeasibilityProgramme viability, trade-offs and resources.
Discovery Red TeamIndependent critique, contradictions and falsification.
Mission room

See how the company would work.

Preview how a company-level mission will coordinate existing BayesArc capabilities. This remains a browser-only frontend demonstration until the orchestration API is connected.

MISSION BUILDER

Frame one scientific objective

This frontend object previews the future company mission contract without writing to Agent OS, Discovery OS, Candidate OS or MIDD.

Frontend preview only · no backend mutation
LIVE COMPANY FLOW

Project Aurora

Ready to simulate a governed workstream.

OpportunityOpportunity Scout
ReasoningAgent OS v2
Scientific stateDiscovery Twin
DecisionHuman review gate
Virtual company frontend previewREADY
01
Chief OrchestratorClassify objective, risk, and required company lanes.
waiting
02
Discovery Programme ManagerBuild the stage-aware scientific DAG and specialist assignments.
waiting
03
Specialist scientist fan-outBiology, chemistry, DMPK, translation, portfolio, and evidence roles work in parallel.
waiting
04
Discovery Red TeamChallenge claims, contradictions, assumptions and missing evidence.
waiting
05
Discovery Twin / Scientific DAGConverge evidence into one traceable programme state.
waiting
06
Human decision gateQualified human decides whether to advance, close gaps, redesign, pause or stop.
waiting
Operating loop

Plan. Spawn. Execute. Challenge. Commit. Decide.

The company should scale through controlled decomposition rather than a single giant agent. Every temporary worker should have a bounded task, evidence contract, budget, and review destination.

01Frame mission

Define objective, programme, decision gate, constraints, and acceptable evidence.

02Plan DAG

Programme Manager decomposes work into scientific dependencies and roles.

03Spawn specialists

Launch bounded specialist workers only where the mission needs parallelism.

04Independent challenge

Red team checks contradictions, unsupported claims, and model applicability.

05Commit evidence

Verified outputs converge into Discovery Twin, Candidate OS, and later MIDD.

06Human authority

Consequential experiment, candidate, dose, trial, and regulatory decisions stay human-owned.

Governed spine

One scientific state across the lifecycle.

The virtual company becomes useful when the swarm does not end in chat. Evidence needs to persist into the programme systems that already govern discovery and development.

Discovery Twin / Scientific DAGHypotheses, evidence dependencies, contradictions, uncertainty, experiments and decisions.
scientific state
↓
BayesArcDiscovery programmes, therapeutic design, generation, docking, ADMET and experiment loops.
discovery
↓
Candidate OSCandidate identity, evidence ledger, trade-offs, decision passport and nomination governance.
candidate
↓
MIDDPopPK, PBPK/PBBM, PK/PD, QSP, dose strategy and trial simulation.
translation
↓
Clinical DevelopmentTrials, biomarkers, endpoints, quantitative evidence and development decisions.
clinical
↓
Regulatory / Safety / LifecycleSubmission evidence, benefit-risk, commitments, post-market learning and lifecycle change.
lifecycle
Scale roadmap

From virtual company to elastic scientific workforce.

The next step is not adding dozens of static agent names. It is building safe hierarchical fan-out and fan-in so temporary workers can process trials, papers, datasets, assays, molecules, and model checks at useful scale.

P0

Unified Virtual Biotech mission contract

One company-level mission identity that references existing Opportunity Scout, Agent OS, Discovery Twin, Candidate OS and MIDD objects.

orchestration API later
P0

Cross-system orchestration

Coordinate existing Agent OS, Discovery OS and scientific services through one mission without changing their current client-facing contracts.

backend later
P1

Mass evidence fan-out

Trial-by-trial, paper-by-paper, dataset-by-dataset and candidate-by-candidate parallel workers.

elastic workers
P1

Fan-in + governed commit

Deduplicate, challenge, rank and commit accepted evidence back into the authoritative programme spine.

review first
BayesPharma virtual biotech

A company of agents — governed like a scientific organization.

This prototype deliberately separates the company concept from live backend execution. When connected later, the same interface can become the mission-control layer for bounded scientific swarms while Discovery Twin, Candidate OS, MIDD and human review remain authoritative.

Open current Agent OS