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Candidate → FIH → SAD → MAD → Phase II → Phase III → submission → post-approval

Clinical Development Command Center

One governed clinical-development record over the same BayesPharma programme and candidate identity. Evidence changes programme state; an AI explanation never does.

Same candidate identityMEASURED / COMPUTED / RETRIEVED / REVIEWEDExplicit phase gatesHuman transition review

Development path

A phase is never advanced by a percentage. All required gates must be satisfied and an accountable human must approve the next transition.

No readiness score

1 · Programme & phase status

Clinical development extends the nominated Discovery Programme candidate; it does not clone the asset into another identity system.

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2 · Study & analysis portfolio

Study plans are workflow objects, not authorization to dose participants. External protocol, ethics, regulatory and site controls remain authoritative.

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Plan a governed study/work package

3 · Clinical evidence matrix

Only human-QC-approved observation imports become MEASURED. Simulations and models remain COMPUTED; registry/publication evidence remains RETRIEVED; accountable decisions remain REVIEWED.

A vendor/CRO/LIMS row claiming “approved” is deliberately downgraded to QC review until a BayesPharma human reviewer explicitly accepts it.

4 · Deterministic clinical blockers

Blockers are derived from explicit evidence and review gates for the current phase, not from Qwen or an opaque readiness score.

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5 · Next Best Clinical Work

Ranking: decision criticality × uncertainty × discriminatory power × probability of changing the decision ÷ cost/time burden. Every recommendation still requires human approval.

Human approval required
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Human phase transition review

Only the next governed phase can be approved. A blocked gate prevents approval server-side.